Speaker(s):

Mark Gold, MD

Presentation:  This presentation will review the early work on drugs, memory, and state dependency of memory and how these relate to slips, relapse, cravings and depression. The link between locus coeruleus to opiate withdrawal and nucleus accumbens to cocaine withdrawal will be described. The dopamine hypothesis and proof of cocaine being addictive led to a change in the DSM diagnosis for addiction and made it possible for gambling and other processes to be addictive. The learner will follow the theory to the development of new treatments for opiate, cocaine, and other addictive processes. The learner will understand how smoking is injection without a needle and how smoking cigarettes or marijuana is like and unlike nicotine or THC.

Objectives:

  • Review the early work on drugs, memory and state dependency of memory and how these relate to slips, relapse, cravings and depression.
  • Discuss the link between locus coeruleus to opiate withdrawal and nucleus accumbens to cocaine withdrawal.
  • Outline the theory to the development of new treatments for opiate, cocaine and other addictive processes.
  • Describe how smoking is injection without a needle and how smoking cigarettes or marijuana is like and unlike nicotine or THC.

Slides:

Gold_Missouri handout

Gold-RYCU April 2017

Gold-RYCU May 2017